Generic Name: Filgrastim
Other Names: G-CSF, Granulocyte - Colony Stimulating Factor

Drug Type:

Neupogen is a biologic response modifier.  It is classified as a colony stimulating factor.  (For more detail, see "How Neupogen Works" section below).
What Neupogen Is Used For:

Note:  If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.

How Neupogen Is Given:

Neupogen Side Effects:

Important things to remember about the side effects of Neupogen:

The following side effects are common (occurring in greater than 30%) for patients taking Neupogen:

Note:  There are no common side effects of Neupogen.

These side effects are less common side effects (occurring in about 10-29%) of patients receiving Neupogen:

Not all side effects are listed above. Some that are rare (occurring in less than 10% of patients) are not listed here.  However, you should always inform your health care provider if you experience any unusual symptoms.

When To Contact Your Doctor or Health Care Provider:

Contact your health care provider immediately, day or night, if you should experience any of the following symptoms:

The following symptoms require medical attention, but are not an emergency. Contact your health care provider within 24 hours of noticing any of the following:

Always inform your health care provider if you experience any unusual symptoms.

Neupogen Precautions: 

Neupogen Self Care Tips:

Monitoring and Testing While Taking Neupogen:

You will be checked regularly by your health care professional while you are taking Neupogen to monitor side effects and check your response to therapy.  Periodic blood work to monitor your complete blood count (CBC) as well as the function of other organs (such as your kidneys and liver) will also be ordered by your doctor.   

How Neupogen Works:

Colony-Stimulating Factors

In the body's bone marrow (the soft, sponge-like material found inside bones) blood cells are produced.  There are three major types of blood cells; white blood cells, which fight infection; red blood cells, which carry oxygen to and remove waste products from organs and tissues; and platelets, which enable the blood to clot.  Cancer treatments such as chemotherapy and radiation therapy can effect these cells which put a person at risk for developing infections, anemia and bleeding problems.  Colony-stimulating factors are substances that stimulate the production of blood cells and promote their ability to function.   They do not directly affect tumors but through their role in stimulating blood cells they can be helpful as support of the persons immune system during cancer treatment.

Neupogen is a growth factor that stimulates the production, maturation and activation of neutrophils. Neupogen also stimulates the release of neutrophils (a type of white blood cell) from the bone marrow.  In patients receiving chemotherapy, Neupogen can accelerate the recovery of neutrophils, reducing the neutropenic phase (the time in which people are susceptible to infections).

Note:  We strongly encourage you to talk with your health care professional about your specific medical condition and treatments. The information contained in this website is meant to be helpful and educational, but is not a substitute for medical advice.